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HNF4-alpha(Phospho Ser313) Polyclonal Antibody, 50ul Sample Library Tubes Genetic variations in this gene

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HNF4-alpha(Phospho Ser313) Polyclonal Antibody, 50ul Sample Library Tubes Genetic variations in this geneThe protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non insulin

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Description

Genetic variations in this gene are associated with susceptibility to leprosy type 4

It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome

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The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression

it protects cells from the growth-inhibiting and/or pro-apoptotic effects of cortisol

HNF4-alpha(Phospho Ser313) Polyclonal Antibody, 50ul Sample Library Tubes Genetic variations in this geneThe protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non insulin

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