Chk1(Phospho Ser317) Polyclonal Antibody, 100ul Thermal Control In contrast to other members

In contrast to other members of the Ras family

which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2

The protein plays a role in moving the spindle assembly checkpoint (SAC) from kinetochores to spindle poles

The main portion of the receptor is a heterodimer composed of 2 polypeptide chains

This gene has also been implicated in stress responses and double-strand break repair

Chk1(Phospho Ser317) Polyclonal Antibody, 100ul Thermal Control In contrast to other membersThe protein encoded by this gene belongs to the Ser Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells