CCNK Polyclonal Antibody, 50ul Vacuum Aspirator Mediator of RNA polymerase II

Mediator of RNA polymerase II transcription subunit 1 encoded by MED1 is a subunit of the CRSP (cofactor required for SP1 activation) complex

This intronless gene may be a pseudogene (PMID:11450850)

The protein encoded by this gene is a DNA N-glycosylase of the endonuclease III family

The enzyme catalyzes the oxidation of sulfite to sulfate| the final reaction in the oxidative degradation of the sulfur amino acids cysteine and methionine

Allelic variants of this gene are associated with microcephaly

CCNK Polyclonal Antibody, 50ul Vacuum Aspirator Mediator of RNA polymerase IIThe protein encoded by this gene is a member of the transcription cyclin family. These cyclins may regulate transcription through their association with and activation of cyclin dependent kinases (CDK) that phosphorylate the C terminal domain (CTD) of the large subunit of RNA polymerase II. This gene product may play a dual role in regulating CDK and RNA polymerase II activities.