Cyclin E2(Phospho Thr392) Polyclonal Antibody, 20ul Site-directed Mutagenesis Alternative splicing of this gene

Alternative splicing of this gene results in distinct isoforms which are likely to have different substrate specificities

The encoded protein is also involved in MAP/ERK signaling pathway in specific cell types

Transcript variants encoding distinct isoforms have been identified

Hypermethylation and transcriptional downregulation of this gene has been observed in oligodendroglial tumors with deletions of chromosomal arms 1p and 19q

It has Catalytic activity for class I and II ArfGAPs in vitro

Cyclin E2(Phospho Thr392) Polyclonal Antibody, 20ul Site-directed Mutagenesis Alternative splicing of this geneThe protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This