LOXL4 Rabbit Polyclonal Antibody, 100ul Cell Culture Isoform 3 may play a

Isoform 3 may play a role in early spermatogenesis

The encoded protein is localized to the cytosol and mitochondria| and associates with membranes through an isoprenyl modification near the C-terminus

and exists as four alternatively spliced isoforms

as indicated for members 1-3

The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule

LOXL4 Rabbit Polyclonal Antibody, 100ul Cell Culture Isoform 3 may play aThis gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue encoding an extracellular copper dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C terminus end appears to be sufficient for amine oxidase activity suggesting that each family member may retain