CCBE1 Polyclonal Antibody, 100ul Custom Peptide Synthesis The 20S core is composed

The 20S core is composed of 4 rings of 28 non-identical subunits

The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex

This particular gene maps to chromosome X in a head-to-head orientation with SPANX family member A2| which appears to be a duplication of the A1 locus

The encoded protein associates with hnRNP proteins and may be involved in regulating alternative splicing

TNF receptor-associated factor 6 encoded by TRAF6 is a member of the TNF receptor associated factor (TRAF) protein family

CCBE1 Polyclonal Antibody, 100ul Custom Peptide Synthesis The 20S core is composedThis gene is thought to function in extracellular matrix remodeling and migration. It is predominantly expressed in the ovary, but down regulated in ovarian cancer cell lines and primary carcinomas, suggesting its role as a tumour suppressor. Mutations in this gene have been associated with Hennekam lymphangiectasia lymphedema syndrome, a generalized lymphatic dysplasia in humans.