PDZK3 Polyclonal Antibody, 100ul Live Cell Imaging In rat| this protein localizes

In rat| this protein localizes to both the ER by a carboxy-terminal peptide sequence and to mitochondria by an amino-terminal targeting signal

Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I)

The protein encoded by this gene is a member of the ros/insulin receptor family of tyrosine kinases

which use CCR5 as a coreceptor

Two transcript variants encoding the same protein have been found for APOL2

PDZK3 Polyclonal Antibody, 100ul Live Cell Imaging In rat| this protein localizesThe PDZ domain containing 2 encoded by PDZD2 contains six PDZ domains and shares sequence similarity with pro interleukin 16 (pro IL 16). Like pro IL 16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis.