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COL12A1 Polyclonal Antibody, 20ul Contamination Detection & Removal It is involved in various

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COL12A1 Polyclonal Antibody, 20ul Contamination Detection & Removal It is involved in variousThis gene encodes the alpha chain of type XII collagen, a member of the FACIT (fibril associated collagens with interrupted triple helices) collagen family. Type XII collagen is a homotrimer found in association with type I collagen, an association that is thought to modify the interactions between collagen I fibrils and the surrounding matrix. Alternatively spliced transcript variants encoding different isoforms have been identified.

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Description

It is involved in various cellular processes

The 27 kDa form has no activity while the 22/25 kDa form can act as activator for collagenase

Diseases associated with MT-ND5 include leber hereditary optic neuropathy and melas syndrome

and functions as an important regulator of multiple signaling pathways in hematopoietic cells

An important paralog of this gene is HCAR3

COL12A1 Polyclonal Antibody, 20ul Contamination Detection & Removal It is involved in variousThis gene encodes the alpha chain of type XII collagen, a member of the FACIT (fibril associated collagens with interrupted triple helices) collagen family. Type XII collagen is a homotrimer found in association with type I collagen, an association that is thought to modify the interactions between collagen I fibrils and the surrounding matrix. Alternatively spliced transcript variants encoding different isoforms have been identified.

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