NOSTN Rabbit Polyclonal Antibody, 20ul Pathway and Network Analysis It is mitogenic for fibroblasts

It is mitogenic for fibroblasts and smooth muscle but not endothelial cells

tissue specificity:Heart and brain

immune response

Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS)

tissue specificity:Has a limited expression profile

NOSTN Rabbit Polyclonal Antibody, 20ul Pathway and Network Analysis It is mitogenic for fibroblastsNitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission inflammatory response and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production endothelial NO synthase (ENOS; MIM 163729) and triggers the translocation of ENOS from the plasma membrane to vesicle like subcellular structures thereby attenuating ENOS dependent NO production.