Tyk 2 Monoclonal Antibody, 100ul Peripheral Blood Separation Tube This protein is necessary for

This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development

Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer

BAR domain proteins have been implicated in endocytosis

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A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E

Tyk 2 Monoclonal Antibody, 100ul Peripheral Blood Separation Tube This protein is necessary forThis gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti viral immunity. A mutation in this gene has been