Cdc25A(Phospho Ser178) Polyclonal Antibody, 50ul Sampling Tubes The sterile ziplock packaging enables

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It has now been found that this gene is involved in the regulation of many NR and non-NR activities

The protein encoded by this gene belongs to the ubiquitin-specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates

This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC)

Cdc25A(Phospho Ser178) Polyclonal Antibody, 50ul Sampling Tubes The sterile ziplock packaging enablesCDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.