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VEGF Receptor 2(Phospho-Tyr1175) Rabbit Polyclonal Antibody, 100ul Drug Development and Evaluation generating multiple processed forms which

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VEGF Receptor 2(Phospho-Tyr1175) Rabbit Polyclonal Antibody, 100ul Drug Development and Evaluation generating multiple processed forms whichVascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor known as kinase insert domain receptor is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF induced endothelial proliferation survival migration tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors

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Description

generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors

The protein contains both SH2 and SH3 domains which are often found in intracellular kinases

The activity of the encoded protein is regulated by polo-like kinase 1

Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1

|Belongs to the Sp1 C2H2-type zinc-finger protein family

VEGF Receptor 2(Phospho-Tyr1175) Rabbit Polyclonal Antibody, 100ul Drug Development and Evaluation generating multiple processed forms whichVascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor known as kinase insert domain receptor is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF induced endothelial proliferation survival migration tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors

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