GLP1R Polyclonal Antibody, 20ul Immuno Plates Runt-related transcription factor 1 (RUNX1)

Runt-related transcription factor 1 (RUNX1) also known as acute myeloid leukemia 1 protein (AML1) or core-binding factor subunit alpha-2 (CBFA2) is a protein that in humans is encoded by the RUNX1 gene

The protein may also play a role in the morphological organization of liver and intestine

Loss of function or expression of ANXA1 has been detected in multiple tumors

Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms

Mutations in PMS2 have been associated with hereditary nonpolyposis colorectal cancer (HNPCC

GLP1R Polyclonal Antibody, 20ul Immuno Plates Runt-related transcription factor 1 (RUNX1)This gene encodes a 7 transmembrane protein that functions as a receptor for glucagon like peptide 1 (GLP 1) hormone, which stimulates glucose induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP 1 and GLP 1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene