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Human Polycystin-1, PKD1 ELISA Kit , 96T Aspirating Pipets Binds to integrin ITGAV:ITGB3 (PubMed:

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Human Polycystin-1, PKD1 ELISA Kit , 96T Aspirating Pipets Binds to integrin ITGAV:ITGB3 (PubMed:Component of a heteromeric calcium permeable ion Channel formed by PKD1 and PKD2 that is activated by interaction between PKD1 and a Wnt family member, such as WNT3A and WNT9B (PubMed: 27214281). Both PKD1 and PKD2 are required for Channel activity (PubMed: 27214281). Involved in renal tubulogenesis (PubMed: 12482949). Involved in fluid flow mechanosensation by the primary cilium in renal epithelium (By similarity). Acts as a regulator of cilium

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Description

Binds to integrin ITGAV:ITGB3 (PubMed: 28302677)

It localizes to the outer membrane of mitochondria

such as DUSP1

but is upregulated upon activation of lymphocytes

It is expressed in the central and peripheral nervous system where it may be involved in increasing oxygen availability and providing protection under hypoxic/ischemic conditions

Human Polycystin-1, PKD1 ELISA Kit , 96T Aspirating Pipets Binds to integrin ITGAV:ITGB3 (PubMed:Component of a heteromeric calcium permeable ion Channel formed by PKD1 and PKD2 that is activated by interaction between PKD1 and a Wnt family member, such as WNT3A and WNT9B (PubMed: 27214281). Both PKD1 and PKD2 are required for Channel activity (PubMed: 27214281). Involved in renal tubulogenesis (PubMed: 12482949). Involved in fluid flow mechanosensation by the primary cilium in renal epithelium (By similarity). Acts as a regulator of cilium

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