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DOCK 180 Polyclonal Antibody, 100ul Culture Media This gene is ubiquitously expressed

SKU: 96345271321

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DOCK 180 Polyclonal Antibody, 100ul Culture Media This gene is ubiquitously expressedDOCK1 encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. Dedicator of cytokinesis protein 1 regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in

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Description

This gene is ubiquitously expressed in adult tissues

Promotes TLR7 and TLR9-dependent production of IFN-beta production in plasmacytoid dendritic cells (pDCs) by facilitating Lys-63-linked ubiquitination of IRAK1

They function as carriers to the cell surface in post-golgi recycling pathways

Four alternatively spliced transcript variants encoding the same protein have been found for this gene

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DOCK 180 Polyclonal Antibody, 100ul Culture Media This gene is ubiquitously expressedDOCK1 encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. Dedicator of cytokinesis protein 1 regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in

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