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PGBD1 product is specifically expressed in the brain

and the truncated form additionally interacts with CCR1 and CCR2

This difference in size is largely due to an increase in the number of subdomains

Cleaves preferentially Lys-6 and Lys-63-linked ubiquitin chains

TM199 Rabbit Polyclonal Antibody, 20ul Culture Plate Inserts Get ready for accurate andThe protein encoded by this gene has been observed to localize to the endoplasmic reticulum (ER) Golgi intermediate compartment (ERGIC) and coat protein complex I (COPI) in some human cells. The encoded protein shares some homology with the yeast protein Vma12. Defects in this gene are a cause of congenital disorder of glycosylation type IIp.