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MAFK Polyclonal Antibody, 20ul In vitro Assessment Many alternatively spliced transcript variants

SKU: 97448399481

4.1
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MAFK Polyclonal Antibody, 20ul In vitro Assessment Many alternatively spliced transcript variantsThe developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2 (nuclear factor erythroid 2). NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, porphobilinogen deaminase (PBGD; MIM 609806) and ferrochelatase (FECH; MIM 612386). NFE2

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Description

Many alternatively spliced transcript variants encoding different isoforms have been described for this gene

It has been suggested that mammaglobin may be a useful marker for breast cancer clinical research

May be involved in neuronal migration

and besides AGE

A serine-rich region promotes activation of the serum response element (SRE)

MAFK Polyclonal Antibody, 20ul In vitro Assessment Many alternatively spliced transcript variantsThe developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2 (nuclear factor erythroid 2). NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, porphobilinogen deaminase (PBGD; MIM 609806) and ferrochelatase (FECH; MIM 612386). NFE2

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