CREB-1(Phospho Thr100) Polyclonal Antibody, 100ul Custom DNA Oligos Increased expression of CASP2 may

Increased expression of CASP2 may play a role in neurodegenerative disorders including Alzheimer's disease

High expression levels of this protein promote the growth of several types of tumors and may be predictive of the chances of recovery of the patient

The encoded protein binds DNA as a monomer

which belongs to the superfamily of intermediate filament (IF) proteins

Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes

CREB-1(Phospho Thr100) Polyclonal Antibody, 100ul Custom DNA Oligos Increased expression of CASP2 mayThis gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms.