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ATP5A Polyclonal Antibody, 50ul Bottle-Top Dispenser an iron overloading disorder predominant

SKU: 97948931320

4.1
USD162.00 USD195.00

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ATP5A Polyclonal Antibody, 50ul Bottle-Top Dispenser an iron overloading disorder predominantATP5A1 encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, using an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi subunit complexes: the soluble catalytic core, F1, and the membrane spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5

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Description

an iron overloading disorder predominant in Caucasians

one of which (named rTSalpha) represents an alternate 3'UTR that is complementary to the 3'UTR and terminal intron of the thymidylate synthase (TS) RNA and down-regulates TS expression

The encoded preproprotein is proteolytically processed to generate the mature lysosomal prolylcarboxypeptidase

Activated by phosphorylation at Thr-838| inhibited by phosphorylation at Ser-966 and Ser-1033

Gene Ontology (GO) annotations related to this gene include transporter activity and transmembrane transporter activity

ATP5A Polyclonal Antibody, 50ul Bottle-Top Dispenser an iron overloading disorder predominantATP5A1 encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, using an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi subunit complexes: the soluble catalytic core, F1, and the membrane spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5

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