Leuprolide acetate furazone exhibiting highly selective profile including

exhibiting highly selective profile including the canine kidney Na(+)

Fluorescein diacetate can be used as a fluorogenic substrate for hGSTP1-1

Marketed by Nucleus) Mepem (Taiwan) Meropen (Japan

InChi: InChI=1S/C24H27N5O2/c1-2-31-23(30)10-14-26-21-17-22(28-24(27-21)20-9-5-6-13-25-20)29-15-11-18-7-3-4-8-19(18)12-16-29/h3-9

Formula: C5H8N6Na2O5S

Leuprolide acetate furazone exhibiting highly selective profile includingLeuprolide acetate is the acetate salt of a synthetic nonapeptide analogue of gonadotropin releasing hormone. Leuprolide binds to and activates gonadotropin releasing hormone (GnRH) receptors. Continuous, prolonged administration of leuprolide in males results in pituitary GnRH receptor desensitization and inhibition of pituitary secretion of follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to a significant decline in