Fraxinellone esylate 4SC-202 was used at 10µM

4SC-202 was used at 10µM final concentration in various in vitro assays

and is also being investigated for potential application against Lassa fever and Ebola virus disease

CAS Number: 950769-58-1

2020 Feb 4

which is the first selective and potent inhibitor of the H3K27 histone demethylases UTX and JMJD3

Fraxinellone esylate 4SC-202 was used at 10µMFraxinellone, a natural product isolated and purified from the root barks of Dictamnus dasycarpus Turcz. with neuroprotective, vasorelaxing, insecticidal, and antimicrobial activities, is a selective blocker of voltage dependent Ca2 channel, while dictamine relaxed the rat aorta by suppressing the Ca2 influx through both voltage dependent and receptor operated Ca2 channels, and can dramatically induce apoptosis of activated peripheral CD4() T cells in